Moderator: Redaktörer
paa skrev:När det gäller metastudier av sjukdomar och medicin, visst är de noggrannare gjorda, eller?
KarlXII skrev:Jag tycker nog att det finns plats för båda angreppssätten.
Det skulle inte förvåna mig om det är helt olika mekanismer i kroppen och knoppen som sätts igång av frågorna "föredrar du" eller "kan du skilja på"..
KarlXII skrev:Det känns som de gav upp. Eller fick de sparken rakt av?
Nate Silver skrev:So here’s another question. What would have happened if just 1 out of every 100 voters shifted from Trump to Clinton? That would have produced a net shift of 2 percentage points in Clinton’s direction. And instead of the map you see above, we’d have wound up with this result in the Electoral College instead:
Wansink ... had never heard the term "p-hacking" until he was accused of it. Wansink hasn’t been able to explain how a set of results from his lab could turn out to be so fundamentally flawed
Almen skrev:KarlXII skrev:Jag tycker nog att det finns plats för båda angreppssätten.
Det skulle inte förvåna mig om det är helt olika mekanismer i kroppen och knoppen som sätts igång av frågorna "föredrar du" eller "kan du skilja på"..
Jo, men först måste man ju veta om de går att skilja på över huvud taget, eller hur? Om man inte kan skilja på H och L så är det ju tämligen meningslöst att försöka utvärdera vilken man föredrar.
Almen skrev:Och här är lite mer om Hr. Wansink: “Mindless Eating,” or how to send an entire life of research into question
idea skrev:Almen skrev:Och här är lite mer om Hr. Wansink: “Mindless Eating,” or how to send an entire life of research into question
Intressant läsning. Påminner avlägset om Gillberg och DAMP-forskningen. Fast Gillberg förstörde ju hellre sitt forskningsmaterial än lät någon annan oberoende gå igenom det. Borde ju kört hela ADHD-forskningen i diket men tydligen var han för stor inom fältet för att bli ifrågasatt.
Almen skrev:Om någon hört talas om Brian Wansink och Cornell's Food Laboratories så är de i trubbel. Eller ja, de är ju i trubbel likafullt. Det där med p-fiskande...
Spoiled ScienceWansink ... had never heard the term "p-hacking" until he was accused of it. Wansink hasn’t been able to explain how a set of results from his lab could turn out to be so fundamentally flawed
Almen skrev:Jag tycker ändå att det är utomordenligt märkvärdigt att han inte ens vad var folk talar om när multipla jämförelser tas upp. Om man aldrig hört talas om Bonferroni borde man... eh, ja, se till att höra talas om honom. Men jag antar att p-värden lätt förblindar den som desperat är ute efter något (på riktigt) signifikant.
Almen skrev:Jag tycker att det är bra att det tas upp till allmän diskussion, i alla fall. Så må några ägg knäckas och huvuden rulla.
The Guardian skrev:Last week James Heathers, a postdoctoral researcher at Northeastern University in Boston, made public the results from a statistical reanalysis of data from the bottomless bowls study that call into question the veracity of the results. Heathers used a technique known as SPRITE (short for Sample Parameter Reconstruction via Iterative Techniques) to investigate whether the descriptive statistics reported in the paper (the number of data points, means and standard deviations) could possibly exist, given (a) assumptions about the distribution of the underlying data, and (b) restrictions on the data that are outlined in the paper. A fuller explanation of SPRITE can be found here, but essentially, the idea is that you give the program a mean, standard deviation and some restrictions (say, ten data points have to have a value of 3), and it produces a set of possible histograms of data that could produce those values. The hope is that some of these histograms follow sensible rules about data – are they normally distributed? Are the minimum and maximum values realistic?
NYT skrev:The study was a landmark, one of the few attempts to rigorously evaluate a particular diet. And the results were striking: A Mediterranean diet, with abundant vegetables and fruit, can slash the risk of heart attacks and strokes.
But now that trial, published in the New England Journal of Medicine in 2013, has come under fire. The authors retracted their original paper on Wednesday and published an unusual “re-analysis” of their data in the same journal.
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Some investigators would assign one person in a household — the wife, for example — to one arm of the study — say, to the group consuming olive oil. Then they would ask other members of the household to share that diet, including them as though they had been randomly assigned to it.
“We realized we had never reported that,” Dr. Martínez-González said.
An omission like that erodes the randomized nature of the trial. Family members are likely to share more than just a diet: If a husband and wife both dodge heart disease, it’s difficult to say that their diet is the only reason.
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A researcher at one of the 11 clinical centers in the trial worked in small villages. Participants there complained that some neighbors were receiving free olive oil, while they got only nuts or inexpensive gifts.
So the investigator decided to give everyone in each village the same diet. He never told the leaders of the study what he had done.
“He did not think it was important,” Dr. Martínez-González said.
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Randomized trials are difficult, other experts agreed, and randomized diet studies so perilous they are seldom attempted.
“These people were naïve,” said Donald Berry, a statistician at MD Anderson Cancer Center in Houston. “They were sloppy and didn’t know they were being sloppy.”
Dr. Berry said he wants to believe the results. He loves nuts and has taken to cooking with extra virgin olive oil.
But he remains unconvinced, because the re-analysis did not solve the study’s problems, he said.
Dr. Bradley Efron, a statistics professor at Stanford University, also was skeptical. The revamped results “wouldn’t convince me to be on a Mediterranean diet,” he said.
Almen skrev:Ah, jag missade det så klart! Kom hem och råkade se sista minuterna (och hörde bl.a. referensen till A Lady...). Det får bli svt play.
Vetenskapens värld - När matematiken avslöjar framtiden
The university said in a statement that a year-long review found that Brian Wansink “committed academic misconduct in his research and scholarship, including misreporting of research data, problematic statistical techniques, failure to properly document and preserve research results, and inappropriate authorship.”
petersteindl skrev:Sådär, nu har jag bevisat att det är godare om man först har mjölk i koppen innan teet hälls på än tvärtom.
Mvh
Peter
Royal Society of Chemistry skrev:Milk should be added before the tea, because denaturation (degradation) of milk proteins is liable to occur if milk encounters temperatures above 75°C. If milk is poured into hot tea, individual drops separate from the bulk of the milk and come into contact with the high temperatures of the tea for enough time for significant denaturation to occur. This is much less likely to happen if hot water is added to the milk.
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